AKAP8

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

A-kinase anchor protein 8 is an enzyme that, in humans, is encoded by the AKAP8 gene.[5][6]

AliasesAKAP8, AKAP 95, AKAP-8, AKAP-95, AKAP95, A-kinase anchoring protein 8
End15,379,815 bp[1]
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AKAP8
Identifiers
AliasesAKAP8, AKAP 95, AKAP-8, AKAP-95, AKAP95, A-kinase anchoring protein 8
External IDsOMIM: 604692; MGI: 1928488; HomoloGene: 4278; GeneCards: AKAP8; OMA:AKAP8 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005858

NM_019774
NM_001357760

RefSeq (protein)

NP_005849

NP_062748
NP_001344689

Location (UCSC)Chr 19: 15.35 – 15.38 MbChr 17: 32.52 – 32.54 Mb
PubMed search[3][4]
Wikidata
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Function

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining it to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is redistributed to distinct locations during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.[6]

Interactions

AKAP8 has been demonstrated to interact with:

References

Further reading

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