AMER1

AMER1
Identifiers
Aliases	AMER1, FAM123B, OSCS, WTX, APC membrane recruitment protein 1
External IDs	OMIM: 300647; MGI: 1919595; GeneCards: AMER1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4YJL, 4YK6, 4YJE
Gene location (Human)
Chr.	X chromosome (human)
End	64,205,708 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	94,488,478 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gastrocnemius muscle; ; ganglionic eminence; ; smooth muscle tissue; ; ventricular zone; ; left ovary; ; right ovary; ; skeletal muscle tissue; ; stromal cell of endometrium; ; right lobe of liver;
	Top expressed in
	Rostral migratory stream; ; umbilical cord; ; internal carotid artery; ; otic vesicle; ; hand; ; lacrimal gland; ; retinal pigment epithelium; ; otolith organ; ; utricle; ; abdominal wall;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphatidylinositol-4,5-bisphosphate binding; beta-catenin binding; protein binding; beta-catenin destruction complex binding; lipid binding;
Cellular component	cytoplasm; cytosol; plasma membrane; intracellular membrane-bounded organelle; membrane; nucleus; nuclear body;
Biological process	regulation of canonical Wnt signaling pathway; adipose tissue development; bone development; mesenchymal cell differentiation involved in kidney development; positive regulation of protein ubiquitination; negative regulation of canonical Wnt signaling pathway; kidney development; anatomical structure development; positive regulation of canonical Wnt signaling pathway; beta-catenin destruction complex assembly; beta-catenin destruction complex disassembly; Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	139285
	72345
	ENSG00000184675
	ENSMUSG00000050332
	Q5JTC6
	Q7TS75
	NM_152424
	NM_175179
	NP_689637
	NP_780388
	Wikidata
View/Edit Human	View/Edit Mouse

APC membrane recruitment protein 1 (AMER1) also known as Wilms Tumor on the X (WTX) is a protein that in humans is encoded by the AMER1 gene.