AMG-1

AMG-1
Identifiers
	IUPAC name (6aR,10aR)-3-(Hept-1-ynyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol;
CAS Number	205746-46-9 ;
PubChem CID	10830874;
ChemSpider	9006174 ;
UNII	Q7S86DY7UF;
ChEMBL	ChEMBL279147 ;
Chemical and physical data
Formula	C23H30O2
Molar mass	338.491 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC=3CC1c2c(O)cc(C#CCCCCC)cc2OC(C)(C)C1CC=3;
	InChI InChI=1S/C23H30O2/c1-5-6-7-8-9-10-17-14-20(24)22-18-13-16(2)11-12-19(18)23(3,4)25-21(22)15-17/h11,14-15,18-19,24H,5-8,12-13H2,1-4H3/t18-,19-/m1/s1 ; Key:PYCLMAJRHLLHNO-RTBURBONSA-N ;
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AMG-1 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ⁸-THC with a rigidified and extended 3-position side chain. AMG-1 is a potent agonist at both CB₁ and CB₂ with moderate selectivity for CB₁, with a K_i of 0.6 nM at CB₁ vs 3.1 nM at CB₂.^[1]^[2]

CAS Number

205746-46-9^N

PubChem CID

10830874

ChemSpider

9006174^Y

UNII

Q7S86DY7UF

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AMG-1

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Identifiers

IUPAC name (6aR,10aR)-3-(Hept-1-ynyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CAS Number	205746-46-9^N
PubChem CID	10830874
ChemSpider	9006174^Y
UNII	Q7S86DY7UF
ChEMBL	ChEMBL279147^Y
Chemical and physical data
Formula	C₂₃H₃₀O₂
Molar mass	338.491 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC=3CC1c2c(O)cc(C#CCCCCC)cc2OC(C)(C)C1CC=3
InChI InChI=1S/C23H30O2/c1-5-6-7-8-9-10-17-14-20(24)22-18-13-16(2)11-12-19(18)23(3,4)25-21(22)15-17/h11,14-15,18-19,24H,5-8,12-13H2,1-4H3/t18-,19-/m1/s1^Y Key:PYCLMAJRHLLHNO-RTBURBONSA-N^Y
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