AP8

AP8
Identifiers
	IUPAC name (2S,3R)-3-cyclopropyl-3-[(2R)-2-[1-[(1S)-1-[5-fluoro-2-(trifluoromethoxy)phenyl]ethyl]piperidin-4-yl]-3,4-dihydro-2H-chromen-7-yl]-2-methylpropanoic acid;
PubChem CID	127053597;
ChemSpider	61712481;
Chemical and physical data
Formula	C30H35F4NO4
Molar mass	549.607 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@@H](C1=C(C=CC(=C1)F)OC(F)(F)F)N2CCC(CC2)[C@H]3CCC4=C(O3)C=C(C=C4)[C@H](C5CC5)[C@H](C)C(=O)O;
	InChI InChI=1S/C30H35F4NO4/c1-17(29(36)37)28(21-4-5-21)22-6-3-19-7-9-25(38-27(19)15-22)20-11-13-35(14-12-20)18(2)24-16-23(31)8-10-26(24)39-30(32,33)34/h3,6,8,10,15-18,20-21,25,28H,4-5,7,9,11-14H2,1-2H3,(H,36,37)/t17-,18-,25+,28-/m0/s1; Key:ADYYYLTWZYYGNX-LJYIQKJHSA-N;

AP8 is an experimental drug which acts as a selective agonist for the free fatty acid receptor FFAR1 (GPR40). It has antiinflammatory and anti-fibrotic effects.^[1]^[2]^[3]

FormulaC₃₀H₃₅F₄NO₄

Molar mass549.607 g·mol⁻¹

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References

Identifiers

IUPAC name (2S,3R)-3-cyclopropyl-3-[(2R)-2-[1-[(1S)-1-[5-fluoro-2-(trifluoromethoxy)phenyl]ethyl]piperidin-4-yl]-3,4-dihydro-2H-chromen-7-yl]-2-methylpropanoic acid
PubChem CID	127053597
ChemSpider	61712481
Chemical and physical data
Formula	C₃₀H₃₅F₄NO₄
Molar mass	549.607 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[C@@H](C1=C(C=CC(=C1)F)OC(F)(F)F)N2CCC(CC2)[C@H]3CCC4=C(O3)C=C(C=C4)[C@H](C5CC5)[C@H](C)C(=O)O
InChI InChI=1S/C30H35F4NO4/c1-17(29(36)37)28(21-4-5-21)22-6-3-19-7-9-25(38-27(19)15-22)20-11-13-35(14-12-20)18(2)24-16-23(31)8-10-26(24)39-30(32,33)34/h3,6,8,10,15-18,20-21,25,28H,4-5,7,9,11-14H2,1-2H3,(H,36,37)/t17-,18-,25+,28-/m0/s1 Key:ADYYYLTWZYYGNX-LJYIQKJHSA-N