APBA3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Amyloid beta A4 precursor protein-binding family A member 3 is a protein that in humans is encoded by the APBA3 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesAPBA3, MGC:15815, X11L2, mint3, amyloid beta precursor protein binding family A member 3
Quick facts Available structures, PDB ...
APBA3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAPBA3, MGC:15815, X11L2, mint3, amyloid beta precursor protein binding family A member 3
External IDsOMIM: 604262; MGI: 1888527; HomoloGene: 3591; GeneCards: APBA3; OMA:APBA3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004886

NM_018758

RefSeq (protein)

NP_004877

NP_061228

Location (UCSC)Chr 19: 3.75 – 3.76 MbChr 10: 81.1 – 81.11 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.[6]

Interactions

APBA3 has been shown to interact with Amyloid precursor protein.[5][7]

References

Further reading

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