APC internal ribosome entry site (IRES)

The APC internal ribosome entry site (IRES) is an RNA element which is located in the coding sequence of the APC gene. APC is a tumour suppressor gene which is associated with the inherited disease adenomatous polyposis coli (APC). It is thought that IRES-mediated translation of APC is important for an apoptotic cascade.^[1]

SymbolIRES_APC

RfamRF00462

RNA typeCis-reg; IRES

DomainEukaryota

Quick facts Identifiers, Symbol ...

APC internal ribosome entry site (IRES)
Predicted secondary structure and sequence conservation of IRES_APC
Identifiers
Symbol	IRES_APC
Rfam	RF00462
Other data
RNA type	Cis-reg; IRES
Domain	Eukaryota
GO	GO:0043022
SO	SO:0000243
PDB structures	PDBe

Close