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AR420626

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CAS Number
AR420626
Identifiers
  • N-(2,5-dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC21H18Cl2N2O3
Molar mass417.29 g·mol−1
3D model (JSmol)
  • CC1=C(C(C2=C(N1)CCCC2=O)C3=CC=CO3)C(=O)NC4=C(C=CC(=C4)Cl)Cl
  • InChI=1S/C21H18Cl2N2O3/c1-11-18(21(27)25-15-10-12(22)7-8-13(15)23)20(17-6-3-9-28-17)19-14(24-11)4-2-5-16(19)26/h3,6-10,20,24H,2,4-5H2,1H3,(H,25,27)
  • Key:GGTYQECCGLBHGS-UHFFFAOYSA-N

AR420626 is an experimental drug which acts as a reasonably potent and highly selective agonist for the free fatty acid receptor FFAR3 (GPR41).[1][2] It has been used to research the role of FFAR3 in various disease processes such as diabetes,[3] asthma,[4] eczema[4] and some forms of cancer,[5] as well as regulation of gastrointestinal hormone release.[6]

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