ARHGAP19

Rho GTPase-activating protein 19 is an enzyme that in humans is encoded by the ARHGAP19 gene.^[5]

AliasesARHGAP19, Rho GTPase activating protein 19

External IDsOMIM: 611587; MGI: 1918335; HomoloGene: 13159; GeneCards: ARHGAP19; OMA:ARHGAP19 - orthologs

Chr.Chromosome 10 (human)^[1]

End97,292,673 bp^[1]

Quick facts Identifiers, Aliases ...

ARHGAP19
Identifiers
Aliases	ARHGAP19, Rho GTPase activating protein 19
External IDs	OMIM: 611587; MGI: 1918335; HomoloGene: 13159; GeneCards: ARHGAP19; OMA:ARHGAP19 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q24.1 Start 97,222,173 bp[1] End 97,292,673 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C3 Start 41,755,027 bp[2] End 41,790,486 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in trigeminal ganglion olfactory bulb secondary oocyte tibial nerve spinal ganglia glomerulus metanephric glomerulus testicle gonad ventricular zone Top expressed in otolith organ utricle sciatic nerve stroma of bone marrow spermatocyte primitive streak lumbar spinal ganglion hand granulocyte spermatid More reference expression data BioGPS n/a
Gene ontology Molecular function GTPase activator activity Cellular component nucleus cytosol plasma membrane intracellular membrane-bounded organelle cytoplasm Biological process positive regulation of GTPase activity signal transduction regulation of small GTPase mediated signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84986 71085 Ensembl ENSG00000213390 ENSMUSG00000025154 UniProt Q14CB8 Q8BRH3 RefSeq (mRNA) NM_032900 NM_001204300 NM_001256423 NM_001163495 NM_027667 RefSeq (protein) NP_001191229 NP_001243352 NP_116289 NP_001156967 NP_081943 Location (UCSC) Chr 10: 97.22 – 97.29 Mb Chr 19: 41.76 – 41.79 Mb PubMed search [3] [4]
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Mutations in the ARHGAP19 gene are linked to an inherited form of Charcot-Marie-Tooth disease^[6].