ARHGEF9
Protein-coding gene in humans
From Wikipedia, the free encyclopedia
Rho guanine nucleotide exchange factor 9 is a protein that in humans is encoded by the ARHGEF9 gene.[5][6][7]
AliasesARHGEF9, COLLYBISTIN, EIEE8, HPEM-2, PEM-2, PEM2, Cdc42 guanine nucleotide exchange factor 9, DEE8
External IDsOMIM: 300429; MGI: 2442233; HomoloGene: 9053; GeneCards: ARHGEF9; OMA:ARHGEF9 - orthologs
Function
ARHGEF9 belongs to a family of Rho-like GTPases that act as molecular switches by cycling from the active GTP-bound state to the inactive GDP-bound state. These proteins are key regulators of the actin cytoskeleton and are involved in cell signaling.[supplied by OMIM][7]