ARID5B
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
AT-rich interactive domain-containing protein 5B is a protein that in humans is encoded by the ARID5B gene.[5][6][7]
Alternative names for this gene include Modulator recognition factor 23.
Genomics
The gene is located on the long arm of chromosome 10 (10q21.2) on the 'plus' strand. It spans 195,261 base pairs in length. It encodes a protein of predicted length and molecular weight of 1188 amino acids and 132.375 kilodaltons respectively.
Clinical importance
Through genome wide association studies (GWAS), some of the single nucleotide polymorphisms (SNPs) located in this gene has been noticed to be significantly associated with susceptibility [8][9][10] as well as treatment outcomes [11] of childhood acute lymphoblastic leukaemia in ethnically diverse populations.
