ARL4A

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

ADP-ribosylation factor-like protein 4A is a protein that in humans is encoded by the ARL4A gene.[5]

AliasesARL4A, ARL4, ADP ribosylation factor like GTPase 4A
End12,690,958 bp[1]
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ARL4A
Identifiers
AliasesARL4A, ARL4, ADP ribosylation factor like GTPase 4A
External IDsOMIM: 604786; MGI: 99437; HomoloGene: 4194; GeneCards: ARL4A; OMA:ARL4A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_212460
NM_001037164
NM_001195396
NM_005738

NM_001039515
NM_007487

RefSeq (protein)

NP_001032241
NP_001182325
NP_005729
NP_997625

NP_001034604
NP_031513

Location (UCSC)Chr 7: 12.69 – 12.69 MbChr 12: 40.06 – 40.09 Mb
PubMed search[3][4]
Wikidata
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Function

ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene.[5]

Interactions

ARL4A has been shown to interact with Karyopherin alpha 2.[6]

References

Further reading

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