ATP:ADP antiporter family
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The ATP:ADP Antiporter (AAA) Family (TC# 2.A.12) is a member of the major facilitator superfamily. Members of the AAA family have been sequenced from bacteria and plants.[1]
One protein from the obligate intracellular bacterial parasite, Rickettsia prowazekii, is of 498 amino acyl residues, and is believed to span the membrane 12 times.[2] The transporter is an obligate exchange translocase specific for ATP and ADP. It functions to take up ATP from the eukaryotic cell cytoplasm into the bacterium in exchange for ADP. The ATP/ADP uniporters can also transport inorganic phosphate, but not ribonucleoside and monophosphates, as well as deoxyribonucleotides.[3][4]