ATP adenylyltransferase
Class of enzymes
From Wikipedia, the free encyclopedia
ATP adenylyltransferase (EC 2.7.7.53) is an enzyme that catalyzes the chemical reaction:
| ATP adenylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.53 | ||||||||
| CAS no. | 96697-71-1 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme characterised from Saccharomyces cerevisiae and Myxococcus xanthus combines adenosine triphosphate and adenosine triphosphate to give Ap4A, with orthophosphate (Pi) as a byproduct.[1][2] Ap4A has been suggested to be an alarmone, a compound produced when an organism is damaged or exposed to heat stress.[3]
This enzyme is a transferase, specifically one transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ADP:ATP adenylyltransferase. Other names in common use include bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming), diadenosinetetraphosphate alphabeta-phosphorylase, adenine triphosphate adenylyltransferase, diadenosine 5',5'"-P1,P4-tetraphosphate alphabeta-phosphorylase, (ADP-forming), and dinucleoside oligophosphate alphabeta-phosphorylase.[4]
