AVN-211

AVN-211
Clinical data
Other names	CD-008-0173
Identifiers
	IUPAC name 5,7-dimethyl-2-(methylsulfanyl)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine;
CAS Number	1173103-84-8;
ChemSpider	26387125;
UNII	L6B63H3RXJ;
ChEMBL	ChEMBL1668500;
CompTox Dashboard (EPA)	DTXSID001032056 ;
Chemical and physical data
Formula	C15H15N3O2S2
Molar mass	333.42 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cc1cc(n2c(n1)c(c(n2)SC)S(=O)(=O)c3ccccc3)C;
	InChI InChI=1S/C15H15N3O2S2/c1-10-9-11(2)18-14(16-10)13(15(17-18)21-3)22(19,20)12-7-5-4-6-8-12/h4-9H,1-3H3; Key:KSAUCBGUWGWPDL-UHFFFAOYSA-N;

AVN-211 (CD-008-0173) is a drug which acts as a highly selective 5-HT₆ receptor antagonist and is under development by Avineuro Pharmaceuticals for the treatment of schizophrenia.^[1]^[2]^[3] In early 2011, it successfully completed phase IIa clinical trials,^[1]^[4] with benefits on positive symptoms and some procognitive effects observed,^[5] and in mid 2013, phase IIb clinical trials for schizophrenia began.^[6] Avineuro Pharmaceuticals also expressed intention to start clinical trials of AVN-211 for Alzheimer's disease in 2015.^[6]^[7]^{[needs update]}