Acetophenone carboxylase

Acetophenone carboxylase (EC 6.4.1.8) is an enzyme with systematic name acetophenone:carbon-dioxide ligase (ADP-forming).^[1] This enzyme catalyses the following chemical reaction

2 ATP + acetophenone + HCO₃⁻ + H₂O + H⁺ ${\displaystyle \rightleftharpoons }$ 2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate

The enzyme is involved in anaerobic degradation of ethylbenzene.