Natchez On-Top-of-the-Hill Historic District

Architecturally, the district includes a set of Greek Revival works that are of national-level significance, and many other styles including Late Victorian architecture.^[2] It has what is assessed to be the best Swiss Chalet Style work in Mississippi and it also has the best residential French Second Empire style work in Mississippi.^[2]: 17

Important sites within the district include:^[2]: 17

• Andrew Marschalk's printing office where the first book printed in Mississippi was printed in 1799,
• the first bank in Mississippi,
• the site of American flag-raising, in 1798, by Andrew Ellicott near the House on Ellicott's Hill, and
• the traditional location of the earliest Sunday school south of Philadelphia, conducted at a Methodist church.

It includes National Historic Landmark-designated sites:^[2]

• House on Ellicott's Hill
• Stanton Hall
• Rosalie
• Commercial Bank and Banker's House (c. 1837), consisting of the Commercial Bank Building, a "one-story three-bay stuccoed brick with stone facade commercial building of two-story height with Ionic portico," and the connected Greek Revival style.^[2]: 83

Other sites individually listed on the National Register include:

• King's Tavern (1769), 611 Jefferson Street
• The Elms (c. 1805), 801 Washington Street
• Adams County Courthouse (c. 1820), 201 S. Wall Street; considered one of the district's "pivotal" contributing buildings, a two-story Federal-style brick courthouse with a cupola. It was remodeled c. 1920 into Colonial Revival style with classical porticos.^[2]: 77
• Presbyterian Manse (c. 1830), 307 S. Rankin Street
• Winchester House (1835), 816 Main Street
• Choctaw (c. 1835), NRHP-listed as Neibert-Fisk House
• The Barnes House (c. 1836)
• First Presbyterian Church (1830), 117 S. Pearl Street
• John Baynton House, (c. 1833), 821 Main Street, NRHP-listed; also known as "Williamsburg"
• Trinity Episcopal Church (1822), Greek Revival, 305 Commerce Street South
• Green Leaves (1838), 303 S. Rankin Street; Greek Revival with doric columns
• William Johnson House (1841) Greek Revival
• Melrose (1848), 1 Melrose-Montebello Parkway^: 84
• Magnolia Hall (1858), 215 S. Pearl Street; NRHP-listed as the Henderson-Britton House
• Longwood (c. 1859), 140 Lower Woodville Road^: 84
• Glen Auburn (c. 1875), 300 S Commerce Street; built by Christian Schwartz, described as "probably the most outstanding of the post-Civil War houses" in the district and as "the best example of the Second Empire style in the state of Mississippi."^[2]
• St. Mary's Cathedral (1882), 107 S. Union Street; also known as St. Mary Basilica
• Prentiss Club (1904), 211 N. Pearl Street; a yellow brick building in Second Renaissance Revival style, designed by New Orleans architects Soule and McDonald
• Temple B'nai Israel (1905), 213 South Commerce Street
• Stratton Chapel of the First Presbyterian Church (1909)

• Notable sites
• 
  The Manse
• 
  Glen Auburn
• 
  Adams County Courthouse
• 
  The Barnes House

A map delineating the area of the district, including a rectangle defined by Monroe, Pine, Orleans, and Broadway, but also a bit more, is provided in its 1979 NRHP nomination document.^[3]

There are several other NRHP-listed historic districts in Natchez:

• Downriver Residential Historic District, adjacent on the south below Orleans St.
• Natchez Bluffs and Under-the-Hill Historic District, adjacent to the river side
• Upriver Residential District, adjacent on the north, above Monroe St.
• Holy Family Catholic Church Historic District, adjacent, on the west
• Clifton Heights Historic District, on the river side of the Upriver Residential District
• Cemetery Bluff District
• Woodlawn Historic District