Adarigiline

Adarigiline (INNTooltip International Nonproprietary Name) is a monoamine oxidase inhibitor (MAOI) that was never marketed.^[1][2][3][4] It is specifically a monoamine oxidase B (MAO-B) inhibitor.^[1][2][3] This drug candidate was first described in 2009, in a patent assigned to Helicon Therapeutics.^[5]

Drug classMonoamine oxidase B (MAO-B) inhibitor

CAS Number

• 1124197-79-0

PubChem CID

• 25211190

ChemSpider

• 64835238

Quick facts Clinical data, Drug class ...

Adarigiline

Clinical data
Drug class	Monoamine oxidase B (MAO-B) inhibitor
Identifiers
IUPAC name (4-hydroxypiperidin-1-yl)-[5-[4-methyl-5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl]methanone
CAS Number	1124197-79-0
PubChem CID	25211190
ChemSpider	64835238
UNII	YRT54V76ZY
Chemical and physical data
Formula	C15H15F3N2O3S
Molar mass	360.35 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=C(ON=C1C2=CC=C(S2)C(=O)N3CCC(CC3)O)C(F)(F)F
InChI InChI=1S/C15H15F3N2O3S/c1-8-12(19-23-13(8)15(16,17)18)10-2-3-11(24-10)14(22)20-6-4-9(21)5-7-20/h2-3,9,21H,4-7H2,1H3 Key:VXBWTNLAIBIATJ-UHFFFAOYSA-N

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