Adenosylcobinamide-phosphate synthase
Class of enzymes
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Adenosylcobinamide-phosphate synthase (EC 6.3.1.10, CbiB) is an enzyme with systematic name adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming).[1][2] This enzyme catalyses the following chemical reaction
- (1) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate ADP + phosphate + adenosylcobinamide phosphate
- (2) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol ADP + phosphate + adenosylcobinamide
| Adenosylcobinamide-phosphate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 6.3.1.10 | ||||||||
| CAS no. | 905988-16-1 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
One of the substrates, (R)-1-aminopropan-2-yl phosphate, is produced by CobD (EC 4.1.1.81). This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in bacteria.
