Wikiwand AI

Aditoprim

Chemical compound From Wikipedia, the free encyclopedia

Aditoprim is an antibacterial dihydrofolate reductase inhibitor.[1] It is currently being investigated for veterinary use, mostly in China for the treatment of various Streptococcus caused conditions.[2][3] A 2025 study found that it is toxic to the human gut microbiota as most antibiotics are, and established a microbiologically acceptable daily intake of 91.67 µg/kg.BW/day.[4]

Quick facts Names, Identifiers ...
Aditoprim
Names
Preferred IUPAC name
5-{[4-(Dimethylamino)-3,5-dimethoxyphenyl]methyl}pyrimidine-2,4-diamine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C15H21N5O2/c1-20(2)13-11(21-3)6-9(7-12(13)22-4)5-10-8-18-15(17)19-14(10)16/h6-8H,5H2,1-4H3,(H4,16,17,18,19)
    Key: QBQMXWZTRRWPGK-UHFFFAOYSA-N
  • InChI=1/C15H21N5O2/c1-20(2)13-11(21-3)6-9(7-12(13)22-4)5-10-8-18-15(17)19-14(10)16/h6-8H,5H2,1-4H3,(H4,16,17,18,19)
    Key: QBQMXWZTRRWPGK-UHFFFAOYAE
  • CN(C)C1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC
Properties
C15H21N5O2
Molar mass 303.366 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Close

References

Related Articles

Timelines

Top Qs

Fact Checks