Adrenergic release inhibitor
Class of antihypertensive drugs
From Wikipedia, the free encyclopedia
Adrenergic release inhibitors are a class of drugs which inhibit the release of epinephrine (adrenaline) and/or norepinephrine (noradrenaline) from adrenergic nerve terminals and are used as antihypertensives.[1][2] Examples of these agents include bethanidine, bretylium, debrisoquine, guanisoquin(7-bromo Debrisoquine), guanadrel, guanazodine, guancydine, guanethidine, guanoclor, and guanoxan.[1][2] Most agents of this class are guanidinium compounds and have little capacity to cross the blood–brain barrier.[2]
