Adrenergic urticaria

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Adrenergic urticaria
SpecialtyDermatology

Adrenergic urticaria is a skin condition characterized by an eruption consisting of small (1-5mm) red macules and papules with a pale halo, appearing within 10 to 15 min after emotional upset.[1]:154[2] There have been 10 cases described in medical literature, and involve a trigger (coffee, intense emotions) followed by a rise in catecholamine and IgE. Treatment involves propranolol and trigger avoidance.[3]

The underlying mechanisms are not fully understood, but existing research suggests that adrenergic urticaria is linked with elevated serum catecholamine levels. The characteristic halo hives are most likely caused by catecholamine-induced peripheral vasoconstriction around erythematous wheals, which is consistent with other types of urticaria.[3]

Diagnosis

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