Agrocybin

Agrocybin is a toxic polyyne amide found in certain mushrooms, notably in the genus Agrocybe (especially Agrocybe dura) and in Marasmius oreades.^[2][3][4] It exhibits cytotoxic, immunosuppressive, trypanocidal, antibacterial, as well as potent antifungal and antiluminescent activities.^[1][5][6]

Quick facts Names, Identifiers ...

Agrocybin

Names
IUPAC name 8-hydroxyocta-2,4,6-triynamide
Other names 8-Hydroxy-2,4,6-octatriynamide 2,4,6-Octatriynamide, 8-hydroxy-
Identifiers
CAS Number	544-44-5
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1967731
ChemSpider	10538
PubChem CID	11004
UNII	A0AFV4JUIT
CompTox Dashboard (EPA)	DTXSID20202786
InChI InChI=1S/C8H5NO2/c9-8(11)6-4-2-1-3-5-7-10/h10H,7H2,(H2,9,11) Key: OXONWCQUZYDTNF-UHFFFAOYSA-N
SMILES C(C#CC#CC#CC(=O)N)O
Properties
Chemical formula	C8H5NO2
Molar mass	147.133 g·mol−1
Appearance	Solid
Melting point	130–140 °C (266–284 °F; 403–413 K)
Hazards
Lethal dose or concentration (LD, LC):
LD50 (median dose)	6 mg/kg (IV, mice) 60 mg/kg (oral, mice)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

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