Szentkirályi holds a law degree from Pázmány Péter Catholic University. She began her political career at Fidelitas, the youth wing of Fidesz party. Between 2007 and 2010, she was the local leader of Fidelitas in the 1st District of Budapest. From 2009, she worked for Nézőpont Institute, a Fidesz-tied pollster, and at the same time she was the staff member responsible for vendor relations at the Budapest Stock Exchange. In 2011, she became the member of Fidesz–KDNP faction of the General Assembly of Budapest.
From 2012 she was a member of the Board of Directors of the Hungarian Football Federation in Budapest, from 2011 to 2014 she was chairwoman of the supervisory board of BKK Közút Zrt., between 2010 and 2012 she was a member of the supervisory board of Budapest Ornamental and Street Lighting Ltd., and between 2010 and 2012 she was a member of the supervisory board of Fővárosi Közterületfenntartó Zrt.[5]
In 2014, she was involved in István Tarlós's campaign for mayor, and from 7 November to 2019 she became the Deputy Mayor of Budapest, overseeing cultural, education, social and youth policy, sports, environment, tourism and image.[6]
Viktor Orbán has appointed her to succeed István Hollik as spokesperson of the Hungarian government from 1 January 2020.[1]
On 14 March 2024, it was announced that she would be the Fidesz party candidate for Mayor of Budapest in the 2024 mayoral election, against opposition mayor Gergely Karácsony.[3] During her activity, Szentkirályi ran an exclusively defamatory campaign against Karácsony, frequently called him as the "puppet" of former prime minister and opposition leader Ferenc Gyurcsány. Under the slogan "Budapest needs change", she tried to prove Karácsony's incompetence in numerous TikTok videos, but she did not publish her own program or vision. Fidesz leaders, including PM Viktor Orbán remained remarkably passive during her campaign, according to analysts, Fidesz priced the defeat in advance. Szentkirályi refused to attend debates against Karácsony and Vitézy, and, with the exception of pro-government media, she did not give any interviews to the media.[7] Karácsony considered Fidesz "official" candidate Szentkirályi will withdraw in favor of Vitézy sometime during the campaign. Both Vitézy and Szentkirályi refused the allegations throughout the campaign.[8] However, Szentkirályi withdrew her candidacy on 7 June, two days before the election and endorsed Vitézy. Pro-government media unanimously encouraged the election of Vitézy, but the support of the Fidesz–KDNP list in the simultaneous General Assembly election.[4]
