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Alizarin Red S

Chemical compound and histologic dye From Wikipedia, the free encyclopedia

Alizarin Red S (also known as C.I. Mordant Red 3, Alizarin Carmine, and C.I 58005.[1]) is a water-soluble sodium salt of Alizarin sulfonic acid with a chemical formula of C
14H
7NaO
7S.[2][1] Alizarin Red S was discovered by Graebe and Liebermann in 1871.[2] In the field of histology alizarin Red S is used to stain calcium deposits in tissues,[3][4] and in geology to stain and differentiate carbonate minerals.[3]

Quick facts Names, Identifiers ...
Alizarin Red S
Chemical structure of Alizarin Red S
Names
IUPAC name
Sodium 3,4-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
Other names
  • Mordant Red 3
  • C.I 58005
  • Sodium alizarinesulfonate
  • Alizarine S
  • Alizarine sulfonate
  • Alizarin Red, water-soluble
  • Alizarin Carmine
  • Alizarin sodium monosulfonate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.004.530 Edit this at Wikidata
EC Number
  • 204-981-8
UNII
  • InChI=1S/C14H8O7S.Na/c15-11-6-3-1-2-4-7(6)12(16)10-8(11)5-9(22(19,20)21)13(17)14(10)18;/h1-5,17-18H,(H,19,20,21);/q;+1/p-1
    Key: HFVAFDPGUJEFBQ-UHFFFAOYSA-M
  • [Na+].Oc1c(O)c2C(=O)c3ccccc3C(=O)c2cc1S([O-])(=O)=O
Properties
C14H7NaO7S
Molar mass 342.253 g/mol
Appearance yellow-orange powder
Soluble in water and ethanol
Hazards
Safety data sheet (SDS)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Uses

Alizarin Red S, as sold for use as a histologic stain.

Alizarin Red S is used in histology and histopathology to stain, or locate calcium deposits in tissues.[1][3][4] In the presence of calcium, Alizarin Red S, binds to the calcium to form a Lake pigment that is orange to red in color.[4] Whole specimens can be stained with Alizarin Red S to show the distribution of bone, especially in developing embryos.[4] In living corals alizarin Red S has been used to mark daily growth layers.[5]

In geology, Alizarin Red S is used on thin sections, and polished surfaces to help identify carbonate minerals which stain at different rates.[6]

See also

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