Alpiropride

Alpiropride (INNTooltip International Nonproprietary Name; brand name Revistel, Rivistel, or Rivestel) is a dopamine D₂ receptor antagonist of the benzamide group related to sulpiride.^{[1][2][3][4][5]} It is described as an antihypertensive agent and has been marketed for use as an antimigraine medication in Portugal.^[1][4][2] The drug was first described by 1980^[1] and was introduced for medical use by 1989.^[4] It remained marketed in Portugal as late as 2000.^[2]

Trade namesRevistel, Rivistel, or Rivestel

Other namesIristel; RIV-2093; RIV2093; RIV 2093; Riv 2093; Riv-2093; Riv2093

Drug classDopamine D₂ receptor antagonist; Antihypertensive agent; Antimigraine agent

CAS Number

• 81982-32-3

Quick facts Clinical data, Trade names ...

Alpiropride

Clinical data
Trade names	Revistel, Rivistel, or Rivestel
Other names	Iristel; RIV-2093; RIV2093; RIV 2093; Riv 2093; Riv-2093; Riv2093
Drug class	Dopamine D2 receptor antagonist; Antihypertensive agent; Antimigraine agent
Identifiers
IUPAC name 4-amino-2-methoxy-5-(methylsulfamoyl)-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]benzamide
CAS Number	81982-32-3
PubChem CID	71253
ChemSpider	64384
UNII	1768UW0XS1
ChEBI	CHEBI:135599
ChEMBL	ChEMBL2104024
CompTox Dashboard (EPA)	DTXSID30868635
ECHA InfoCard	100.072.585
Chemical and physical data
Formula	C17H26N4O4S
Molar mass	382.48 g·mol−1
3D model (JSmol)	Interactive image
SMILES CNS(=O)(=O)C1=C(C=C(C(=C1)C(=O)NCC2CCCN2CC=C)OC)N
InChI InChI=1S/C17H26N4O4S/c1-4-7-21-8-5-6-12(21)11-20-17(22)13-9-16(26(23,24)19-2)14(18)10-15(13)25-3/h4,9-10,12,19H,1,5-8,11,18H2,2-3H3,(H,20,22) Key:QRQMZZNDJGHPHZ-UHFFFAOYSA-N

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