Aluminium citrate
Chemical compound
From Wikipedia, the free encyclopedia
Aluminium citrate is a chemical compound with the chemical formula AlC
6H
5O
7. This white, crystalline salt is produced by mixing aluminium chloride hexahydrate and citric acid.[1]
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 Aluminium citrate | |
| Names | |
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| IUPAC name
Aluminium 2-hydroxypropane-1,2,3-tricarboxylate | |
Other names
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| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
| ECHA InfoCard | 100.045.881 |
| EC Number |
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PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C6H5AlO7 | |
| Molar mass | 216.081 g·mol−1 |
| Appearance | White solid |
| Insoluble | |
| Pharmacology | |
| Pharmacokinetics: | |
| Kidney | |
| Hazards | |
| GHS labelling: | |
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| Warning | |
| H302, H315, H319, H373 | |
| P260, P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P314, P321, P330, P332+P313, P337+P313, P362, P501 | |
| Related compounds | |
Other anions |
Aluminium acetate |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Uses
Aluminium citrate can be used as a crosslinker for many polymers in the oil industry.[2] It is also used as an antiperspirant.
Effects on humans
Aluminium citrate takes up about 8% of aluminium in blood[3] due to the ability of Al3+ ions to replace Ca2+ from calcium citrate and is known to cause chronic renal failure because it causes an increase of phosphorus in the kidneys.[4] It has been suspected to cause Alzheimer's disease but more evidence is needed.[5] This compound can also have some positive effects on humans such as preventing silicosis.[6] When ingested, 80% of the compound is excreted through the body through urine and the rest comes out slower.[3]
Aluminium citrate complexes
Aluminium citrate can form complexes such as ammonium aluminium citrate ((NH4)4Al3C6H4O7(OH)(H2O)), which can be created by mixing aluminium nitrate nonahydrate, citric acid, and ammonium hydroxide.[7]