Amine oxidase
Enzyme
From Wikipedia, the free encyclopedia
An amine oxidase is an enzyme that catalyzes the oxidative cleavage of alkylamines into aldehydes and ammonia:[1]
- RCH2NH2 + H2O + O2 RCHO + NH3 + H2O2
Amine oxidases are divided into two subfamilies based on the cofactor they contain:
| Class | Cofactor | Subclass | Enzyme Commission number | Human genes |
|---|---|---|---|---|
| Amine oxidase (formerly EC 1.4.3.6) | copper | lysyl oxidase | EC 1.4.3.13 | LOX |
| primary-amine oxidase | EC 1.4.3.21 | AOC2, AOC3 | ||
| diamine oxidase | EC 1.4.3.22 | AOC1 | ||
| Monoamine oxidase | flavin | N/A | EC 1.4.3.4 | MAOA, MAOB |
