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Aminoadipate-semialdehyde dehydrogenase

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene.[5]

AliasesAASDH, ACSF4, LYS2, NRPS1098, NRPS998, aminoadipate-semialdehyde dehydrogenase
End56,387,508 bp[1]
Quick facts AASDH, Identifiers ...
AASDH
Identifiers
AliasesAASDH, ACSF4, LYS2, NRPS1098, NRPS998, aminoadipate-semialdehyde dehydrogenase
External IDsOMIM: 614365; MGI: 2442517; HomoloGene: 71711; GeneCards: AASDH; OMA:AASDH - orthologs
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
1.2.1.31
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_173765
NM_001377004

RefSeq (protein)

NP_776126
NP_001363933

Location (UCSC)Chr 4: 56.34 – 56.39 MbChr 5: 77.02 – 77.05 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the non-ribosome peptide synthetase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4'phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues.

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