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Angiomotin-like protein 1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Angiomotin-like protein 1 is a protein that in humans is encoded by the AMOTL1 gene.[5][6]

AliasesAMOTL1, JEAP, angiomotin like 1
End94,876,748 bp[1]
Quick facts AMOTL1, Identifiers ...
AMOTL1
Identifiers
AliasesAMOTL1, JEAP, angiomotin like 1
External IDsOMIM: 614657; MGI: 1922973; GeneCards: AMOTL1
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001301007
NM_130847

NM_001081395

RefSeq (protein)

NP_001287936
NP_570899
NP_570899.1

NP_001074864

Location (UCSC)Chr 11: 94.71 – 94.88 MbChr 9: 14.45 – 14.56 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.[6]

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