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Angiopoietin 4

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Angiopoietin-4 is a protein that in humans is encoded by the ANGPT4 gene.[5][6][7]

AliasesANGPT4, AGP4, ANG-3, ANG4, ANG3, angiopoietin 4
End916,334 bp[1]
Quick facts ANGPT4, Identifiers ...
ANGPT4
Identifiers
AliasesANGPT4, AGP4, ANG-3, ANG4, ANG3, angiopoietin 4
External IDsOMIM: 603705; MGI: 1336887; GeneCards: ANGPT4
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015985
NM_001322809

NM_009641

RefSeq (protein)

NP_001309738
NP_057069

NP_033771

Location (UCSC)Chr 20: 0.87 – 0.92 MbChr 2: 151.75 – 151.79 Mb
PubMed search[3][4]
Wikidata
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Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells.

The protein encoded by this gene functions as an agonist and is an angiopoietin.[7]

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