Anidoxime

Anidoxime was an experimental drug that had been evaluated for use as an oral analgesic.^[1][2]

Other namesBamoxine, BRL 11870, E 142, USV-E 142.

CAS Number

• 34297-34-2 23654-53-7

PubChem CID

• 35884

ChemSpider

• 4514617

Quick facts Clinical data, Other names ...

Anidoxime

Clinical data
Other names	Bamoxine, BRL 11870, E 142, USV-E 142.
Identifiers
IUPAC name 3-(Diethylamino)-1-phenyl-1-propanone O-(4-methoxyphenyl)aminocarbonyloxime
CAS Number	34297-34-2 23654-53-7
PubChem CID	35884
ChemSpider	4514617
UNII	88ETS2Q7LZ
CompTox Dashboard (EPA)	DTXSID40865711
Chemical and physical data
Formula	C21H27N3O3
Molar mass	369.465 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN(CC)CCC(=NOC(=O)NC1=CC=C(C=C1)OC)C2=CC=CC=C2
InChI InChI=1S/C21H27N3O3/c1-4-24(5-2)16-15-20(17-9-7-6-8-10-17)23-27-21(25)22-18-11-13-19(26-3)14-12-18/h6-14H,4-5,15-16H2,1-3H3,(H,22,25) Key:XPHBRTNHVJSEQD-UHFFFAOYSA-N

Close

The name is an eponym of an anisdine group and an oxime. The analgesic properties are reportedly equipotent to or greater than morphine but the physical dependence liability may be less.^[3]

In rats, the major metabolic pathway is hydrolysis of the carbamoyl group followed by decarboxylation.^[4]