Khyzhniak was born on 28 July 1990 in the city of Ukrainka in Kyiv Oblast.[2] In 2012, she graduated from the Kyiv National I. K. Karpenko-Kary Theatre, Cinema and Television University. After her studies, Khizhnyak worked at the Kyiv Academic Puppet Theatre.[2] She has dubbed and voiced in Ukrainian and is the official Ukrainian voice of Daisy Ridley and Alicia Vikander. On 2 March 2020, the premiere of the television series "To Catch the Kaidash" took place, in which Khyzhniak played Motrya Kaidash.[2]
Khyzhniak is divorced and has a son.[3][4]
On 26 June, a promotional video for Donald Trump's controversial bill, the One Big Beautiful Bill Act, appeared on the White House's social media accounts. It features Ukrainian actress Antonina Khizhnyak, star of the series ‘Catching Kaidas.’ The actress was surprised to find herself in the video, as it turned out she had previously modelled for stock photo and video websites. [5]