Anuroctoxin
From Wikipedia, the free encyclopedia
Anuroctoxin is a peptide which is derived from the scorpion Anuroctonus phaiodactylus; this scorpion belongs to the scorpion family Iuridae.
Chemistry
Scorpion toxins acting on K+ channels (KTx) are grouped in three different families: the α-,β- and γ-scorpion toxins.[2] The Anuroctoxin peptide belongs to the α-KTx group,[1] which are short peptides that block potassium channels, consisting of 30 to 40 amino acids with three or four disulfide bridges.[3] Based on a phylogenetic analysis Anuroctoxin is included in subfamily six in the α-KTx phylogenetic tree; its systematic name is α-KTx 6.12.[1]
Structure
Anuroctoxin has 35 amino acids with four disulfide bridges. Its molecular weight is 4082.8 Da.[1]
