Apocrine nevus
Medical condition
From Wikipedia, the free encyclopedia
An Apocrine nevus is an extremely rare cutaneous condition that is composed of hyperplastic mature apocrine glands.[1]: 775 Apocrine nevi present as a nodular skin-coloured lump. They are typically asymptomatic. Apocrine nevi can be congenital and they have been associated with other disorders.
| Apocrine nevus | |
|---|---|
| Other names | Apocrine gland hamartoma |
| Specialty | Medical genetics  |
Signs and symptoms
Apocrine nevi manifests as a persistent pedunculated or nodular skin-coloured axillary lump.[2] Additionally, reports of them occurring on the face,[3][4] scalp,[5] chest,[6] and inguinal area have been made.[7] The majority of the time, apocrine nevi are asymptomatic, although some individuals describe minor pain, baldness, or in rare cases, leakage.[8][9]
Causes
Apocrine nevi may be congenital.[9] There have been reported associations with neurofibromatosis,[6] epilepsy,[8] and localized dermal hypoplasia, but these may be coincidental.[10]
Diagnosis
According to histopathology, apocrine nevi are made up of several mature apocrine sweat glands grouped in lobules that invade the dermis and/or hypodermis and cause normal skin structures to be displaced. There may be some cystic dilatation of the lumina in these glands.[11]