Aprobarbital

Aprobarbital (or aprobarbitone), sold under the brand names Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic, and anticonvulsant properties, and was used primarily for the treatment of insomnia.^[2] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed. It has been largely replaced by newer drugs with a better safety margin.

Trade namesOramon, Somnifane, Allonal

Other namesaprobarbitone, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid

AHFS/Drugs.comInternational Drug Names

Drug classBarbiturate

Quick facts Clinical data, Trade names ...

Aprobarbital

Clinical data
Trade names	Oramon, Somnifane, Allonal
Other names	aprobarbitone, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid
AHFS/Drugs.com	International Drug Names
Drug class	Barbiturate
ATC code	N05CA05 (WHO)
Legal status
Legal status	BR: Class B1 (Psychoactive drugs)[1] CA: Schedule IV
Identifiers
IUPAC name 5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
CAS Number	77-02-1 Y
PubChem CID	6464
DrugBank	DB01352 Y
ChemSpider	6221 Y
UNII	Q0YKG9L6RF
KEGG	D00698 Y
ChEBI	CHEBI:2791 Y
ChEMBL	ChEMBL7863 Y
CompTox Dashboard (EPA)	DTXSID8022616
ECHA InfoCard	100.000.908
Chemical and physical data
Formula	C10H14N2O3
Molar mass	210.233 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1NC(=O)NC(=O)C1(C(C)C)C\C=C
InChI InChI=1S/C10H14N2O3/c1-4-5-10(6(2)3)7(13)11-9(15)12-8(10)14/h4,6H,1,5H2,2-3H3,(H2,11,12,13,14,15) Y Key:UORJNBVJVRLXMQ-UHFFFAOYSA-N Y
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