Axial osteosclerosis
Bone disorder
From Wikipedia, the free encyclopedia
Axial osteosclerosis, also known as osteomesopyknosis, is a bone disorder that causes osteosclerosis on the axial spine, pelvis and proximal part of the long bones. It is an autosomal-dominant disease. As of 2024, the exact causes were unknown.[1]
Other namesOsteomesopyknosis
| Axial osteosclerosis | |
|---|---|
| Other names | Osteomesopyknosis |
| Specialty | Orthopedics, medical genetics |
Population estimation
Fewer than 1000 people have this bone disorder in the United States.[1]
Symptoms
This bone disorder can begin to appear in the first years of life, as well as in adulthood.[1] It may present with thoracic pain,[2] kyphosis, scoliosis, vertebral body sclerosis, increased bone density, as well as abnormalities in the cortical bone and vertebrae.[1]