BNIP3L

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like is a protein that in humans is encoded by the BNIP3L gene.[4][5][6]

AliasesBNIP3L, BNIP3a, NIX, BCL2/adenovirus E1B 19kDa interacting protein 3-like, BCL2 interacting protein 3 like
End26,505,636 bp[1]
Quick facts Identifiers, Aliases ...
BNIP3L
Identifiers
AliasesBNIP3L, BNIP3a, NIX, BCL2/adenovirus E1B 19kDa interacting protein 3-like, BCL2 interacting protein 3 like
External IDsOMIM: 605368; MGI: 3642435; HomoloGene: 3195; GeneCards: BNIP3L; OMA:BNIP3L - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004331
NM_001330491

XM_036157725

RefSeq (protein)

NP_001317420
NP_004322
NP_004322.1

n/a

Location (UCSC)Chr 8: 26.38 – 26.51 Mbn/a
PubMed search[2][3]
Wikidata
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Function

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. The protein encoded by this gene is a functional homolog of BNIP3, a proapoptotic protein. This protein may function simultaneously with BNIP3 and may play a role in tumor suppression.[6]

Interactions

BNIP3L has been shown to interact with STEAP3.[7]

References

Further reading

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