Bandicoot papillomatosis carcinomatosis virus
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Bandicoot papillomatosis carcinomatosis viruses are a pair of circular double-stranded DNA virus isolated from bandicoots (Perameles bougainville). The genomes have features similar to viruses in the families Papillomaviridae and the Polyomaviridae. Two strains have been described to date, bandicoot papillomatosis carcinomatosis virus 1 and bandicoot papillomatosis carcinomatosis virus 2.[1]
The genome is ~7.5 kilobases in length[2] with a G+C content of ~35%. Two structural genes are present: L1 and L2. The non structural genes are found on the opposite strand. The L1 gene encodes a protein with 506 residues and the L2 encodes a protein with 470 residues. The two non structural genes T (742 amino acid residues) and t (224 amino acid residues).[3] The capsid proteins resemble those of marsupial papillomaviruses while the T and t antigens resemble those of the avian polyomaviruses.[4]