On 6 January, the junta launched an offensive all across Kayah State. Fighting broke out in Loikaw, Demoso, and Phruso townships, and in Loikaw city, battles occurred at the intersection of Kayentharya road. The 2nd Battalion of the KNDF claimed that in the Kayentharya road skirmish, 15 junta troops were killed, and there were no losses for the KNDF or PDF. At the same time, Karenni Democratic Front and GZ-21 fighters ambushed junta troops at Loikaw University's school of Technology, injuring ten junta troops with no KDF-GZ losses. Junta troops shot and injured two civilians in response. Armored junta vehicles were also seen heading towards Demoso township to aid the junta's offensive.[23] The clashes in Loikaw continued into the next morning, particularly in Myung Ward and the village of Pankan. In Myung Ward, two people were killed and four were injured in the crossfire of the battle, and near the headquarters of the KNPP, seven people were injured. The junta also reportedly bombed the city with planes, a rare occurrence in Kayah State.[24] Six civilians were killed in the fighting on 7 January, according to the KNDF.[25] After the battle began, Loikaw shut down entirely. All administrative and government offices were vacated, and the Loikaw hospital, along with its patients and workers, moved to Taunggyi.[26]
Residents of Loikaw claimed that "there was nowhere to flee", and the offensive caused half of Kayah State to become internally displaced. In Pankan, fierce battles between the KNDF and junta troops caused the deaths of two civilians who couldn't be evacuated in time.[27] On 8 January, the junta continued airstrikes on Loikaw, and urban fighting continued in Minelon Ward and Pankan.[25] Some PDF were injured and killed in the attacks.[25][28] In the fighting on 8 January, the KNDF claimed 30 junta soldiers were killed, including a major, and one tank and one helicopter was damaged.[28] After the clashes on 8 January, the junta retreated back into villages closer to Shan state and Demoso township.[29]
Refugees fleeing Loikaw and heading to Shan State stated that traffic jams were prevalent, and the junta-controlled roads demanded money for vehicle inspections in order to pass.[30] A skirmish on 11 January injured one KDF soldier and an unknown amount of junta troops.[31] While there were no air raids over Loikaw on 11 January, tensions between KDF, KNDF, and PDF against the 250-man garrison of junta troops was high.[31] Evacuation routes also opened up.[31] The KNDF warned that civilians should not go near long rows of villages due to the chance of fighting breaking out.[32] That same day, a battle in Loikaw destroyed the church in Doukhu ward.[33] Fighting in Doukhu ward continued into the evening, along with the fighting in Minelon and My Lo wards.[33] A deputy battalion commander in the Loikaw PDF claimed that the junta suffered casualties during the battle.[33]
On 12 January, Burmese junta planes attacked KNDF-PDF positions near Loikaw, but the KNDF alleged the attacks missed. The militia also claimed that around 20 junta troops were killed during the battle on 12 January, which occurred in the mines and village line. Much of these areas were empty of civilians.[34] By mid-January, 75% of Loikaw's population had fled, mainly towards Shan State.[35] The KNDF claimed on 13 January that during a battle at Minelon Technical University, several junta soldiers were killed and there was nobody to pick up the casualties.[36] Three PDF were killed by land mines in a separate incident, and one civilian was shot dead.[37]
Fighting paused between 14 and 15 January, and restarted again in Myung Ward on 16 January.[38] The KNDF estimated 20 junta soldiers were injured in the fighting.[38] Clashes restarted on 19 January in Doukhu ward, where the KNDF claimed to kill 15 junta soldiers.[39] Junta general Zaw Min Tun (not to be confused with Zaw Myo Tin) claimed that while PDF and KNDF were attacking junta bases and offices in Loikaw, the junta did not suffer any casualties.[40] On 21 January, residents of Loikaw discovered thirteen bodies in Myung ward.[41] The NGO that discovered them stated that intense fighting was taking place in Myung Ward and in the six-mile village near Loikaw.[41] A junta air attack on 24 January killed at least two people in Loikaw as well.[42]
Throughout Loikaw township, a family of six and one man were killed in two separate villages on 29 January, and in Loikaw city, two bodies were discovered in a junta-controlled part of the city. Many of the bodies were found tied up and killed, some in toilets. A Loikaw resident claimed that during his time under junta occupation, junta troops said "neighborhoods would be cleared", and suggested there were more missing bodies.[22]
Fighting had cooled down by 3 February, and residents described the situation as quiet in the day and fighting taking place at night.[43] On 1 February, Lieutenant General Soe Win visited Kayah State and sacked the leader of Kayah State, replacing him with Zaw Myo Tin.[43] The sacking occurred because the KNDF controlled 90% of Kayah State, with the exception of major cities like Bawlakhe, Hpruso, and parts of Loikaw and Demoso and the major roads.[43] Soe Win visited Loikaw on 4 February, meeting with religious leaders. He also visited the Loikaw prison, where the Karenni Army attacked in January, and spoke with police officers. Security was tightened, and residents claimed to have seen fighter jets during the visit. The KNDF criticized the visit.[44]
On 7 February, a KNDF ambush killed seven junta troops in Kayeng Thayar, in eastern Loikaw township.[45] While there was still fighting in Loikaw City, much of it had died down by February to the point refugees began to return. Most battles fought were ambushes, and took place on the city limits and in villages in the township.[46][47] On 9 February, three children were killed in a junta bombing in the village of Le Thu.[48]