Bendazac

Chemical compound From Wikipedia, the free encyclopedia

Bendazac (or bendazolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.[1]

ATC code
Quick facts Clinical data, AHFS/Drugs.com ...
Bendazac
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Topical
ATC code
Identifiers
  • [(1-benzyl-1H-indazol-3-yl)oxy]acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.039.594 Edit this at Wikidata
Chemical and physical data
FormulaC16H14N2O3
Molar mass282.299 g·mol−1
3D model (JSmol)
  • O=C(O)COc2nn(c1ccccc12)Cc3ccccc3
  • InChI=1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20) checkY
  • Key:BYFMCKSPFYVMOU-UHFFFAOYSA-N checkY
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Synthesis

Principal action is inhibition of protein denaturation.

Bendazac synthesis: BE 699226; G. Palazzo, U.S. patent 3,470,194 (1967, 1969 both to Francesco Angelini).

Use of 3-chloro-N,N-dimethylpropanamine in the alkylation step produces benzydamine instead.

See also

References

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