Benzophenone synthase
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Benzophenone synthase (EC 2.3.1.151) is an enzyme that catalyzes a chemical reaction which takes one unit of 3-hydroxybenzoyl-CoA and combines this with three units of malonyl-CoA to give the benzophenone, 2,3',4,6-tetrahydroxybenzophenone, as product. Four units of coenzyme A and three of carbon dioxide are byproducts. The enzyme was characterised from the plant Centaurium erythraea. The product is an intermediate in the biosynthesis of xanthones.[1]
| Benzophenone synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.151 | ||||||||
| CAS no. | 175780-21-9 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase.[2]