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Benzophenone synthase

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Benzophenone synthase (EC 2.3.1.151) is an enzyme that catalyzes a chemical reaction which takes one unit of 3-hydroxybenzoyl-CoA and combines this with three units of malonyl-CoA to give the benzophenone, 2,3',4,6-tetrahydroxybenzophenone, as product. Four units of coenzyme A and three of carbon dioxide are byproducts. The enzyme was characterised from the plant Centaurium erythraea. The product is an intermediate in the biosynthesis of xanthones.[1]

3-hydroxybenzoyl-CoA
+ 3
 
 
 
3 CO2
Rightward reaction arrow with minor product(s) to top right
 
 
 
2D representation of the chemical structure of Q27098205.
2,3',4,6-tetrahydroxybenzophenone
 

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase.[2]

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