Biotene
From Wikipedia, the free encyclopedia
Biotene (typeset as Biotène) is an over-the-counter dental hygiene product currently marketed by Haleon (previously by GSK plc). It is available in various forms, including toothpaste, mouthwash, and gel.
Regular
The main active ingredient in Biotène toothpaste is sodium monofluorophosphate. Prior to the GSK acquisition, it also contained enzymes such as glucose oxidase, lactoferrin, lactoperoxidase, and lysozyme.
PBF (discontinued)
The Plaque Biofilm (PBF) product line contained additional enzymes, including mutanase, dextranase, lysozyme, lactoperoxidase, and glucose oxidase.[1]
Benefits
People with xerostomia (dry mouth) may use Biotène to reduce the recurrence of dental plaque. However, Biotène alone does not significantly reduce the count of Streptococcus mutans, the primary bacterium responsible for the formation of dental plaque.[2]
Biotène claims to relieve symptoms of dry mouth by providing moisture. Dry mouth can be caused by various factors affecting the salivary glands.[3] By keeping the mouth moisturized, Biotène helps prevent complications associated with prolonged dry mouth. For example, dry mouth impairs the antimicrobial properties of saliva, increasing the risk of opportunistic infections.[3] Additionally, by improving the lubrication of the oropharyngeal mucosa, Biotène can facilitate swallowing and reduce the likelihood of developing dysphagia.[4] A 2017 pilot study found that perceived swallowing effort significantly decreased following the application of a saliva substitute.[4]
Biotène compensates for decreased salivary function. A lack of saliva compromises the composition and beneficial properties necessary for maintaining the health of the oral cavity, reducing antibacterial action and disrupting the oral pH. This disruption allows cariogenic microorganisms to grow and colonize the oral cavity.[5] When stimulation of salivary secretion fails, palliative oral care in the form of mouthwashes and saliva substitutes, such as Biotène, can help counterbalance the lack of natural salivary function. Various saliva substitutes containing different enzymes, like those found in Biotène products, help reduce oral infections and enhance mouth wetting.[6] Biotène mouth rinses have shown inhibitory effects on the growth of preformed biofilms on certain tested bacterial and fungal strains.[3][5] However, Biotène does not act through mechanisms that prevent plaque build-up or antimicrobial chemotherapeutic action.[5]
Biotène brand products
The product line includes toothpaste, mouthwash, spray, and gel.
