Bromerguride

Bromerguride
Clinical data
Other names	2-Bromolisuride; 2-Br-LIS; Βromolisuride; Bromuride; ZK-95451; 3-(2-Βromo-9,10-didehydro-6-methyl-8α-ergolinyl)-1,1-diethylurea
Identifiers
	IUPAC name 3-[(6aR,9S)-5-bromo-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea;
CAS Number	83455-48-5;
PubChem CID	71266;
ChemSpider	64394;
UNII	HX58M2377W;
ChEMBL	ChEMBL2104211;
CompTox Dashboard (EPA)	DTXSID70232356 ;
Chemical and physical data
Formula	C20H25BrN4O
Molar mass	417.351 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=C(NC4=CC=CC(=C34)C2=C1)Br)C;
	InChI InChI=1S/C20H25BrN4O/c1-4-25(5-2)20(26)22-12-9-14-13-7-6-8-16-18(13)15(19(21)23-16)10-17(14)24(3)11-12/h6-9,12,17,23H,4-5,10-11H2,1-3H3,(H,22,26)/t12-,17+/m0/s1; Key:SBHNNNRQZGYOAU-YVEFUNNKSA-N;

Bromerguride (INNTooltip International Nonproprietary Name), also known as 2-bromolisuride, is an antidopaminergic and serotonergic agent of the ergoline group which was described as having atypical antipsychotic properties but was never marketed.^[1]^[2]^[3]^[4]^[5] It was the first antidopaminergic ergoline derivative to be discovered.^[1] The pharmacodynamic actions of bromerguride are said to be "reversed"^[jargon] relative to its parent compound lisuride, a dopaminergic agent.^[6]