Buffalo Slough
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| Buffalo Slough | |
|---|---|
  Buffalo Slough  Buffalo Slough | |
| Location | Lake County, South Dakota |
| Coordinates | 43°52′27″N 96°56′20″W / 43.8743°N 96.9390°W |
| Basin countries | United States |
| Surface area | 624 acres (2.53 km2)[1] |
| Designated | 1980 |
Buffalo Slough is a glacial prairie pothole wetland, and adjacent patch of bluestem tallgrass prairie, in Lake County, South Dakota, United States. The complex is located near Chester in far eastern South Dakota. Owned by the State of South Dakota, the formation was listed as a National Natural Landmark in 1980.