Gemeprost
Chemical compound
From Wikipedia, the free encyclopedia
Gemeprost (16, 16-dimethyl-trans-delta2 PGE1 methyl ester) is an analogue of prostaglandin E1.
Trade namesCervagem
Other namesmethyl (E)-7-[(1R,2S,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyl-oct-1-enyl]-5-oxo-cyclopentyl]hept-2-enoate
Pregnancy
category
category
- AU: B3
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| Trade names | Cervagem |
| Other names | methyl (E)-7-[(1R,2S,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyl-oct-1-enyl]-5-oxo-cyclopentyl]hept-2-enoate |
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| Routes of administration | Pessary |
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| ECHA InfoCard | 100.058.869 |
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| Formula | C23H38O5 |
| Molar mass | 394.552 g·mol−1 |
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Clinical use
It is used as a treatment for obstetric bleeding.[citation needed]
It is used with mifepristone to terminate pregnancy up to 24 weeks gestation.[2]
Side effects
Vaginal bleeding, cramps, nausea, vomiting,[3] loose stools or diarrhea,[3] headache, muscle weakness; dizziness; flushing; chills; backache; dyspnoea; chest pain; palpitations and mild pyrexia.[3] Rare: Uterine rupture, severe hypotension, coronary spasms with subsequent myocardial infarctions.[citation needed]
