C6orf62
From Wikipedia, the free encyclopedia
| C6orf62 | |||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | C6orf62, Nbla00237, XTP12, dJ30M3.2, chromosome 6 open reading frame 62 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | MGI: 2441726; HomoloGene: 11551; GeneCards: C6orf62; OMA:C6orf62 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Chromosome 6 open reading frame 62 (C6orf62), also known as X-trans-activated protein 12 (XTP12),[5] is a gene that encodes a protein of the same name. The encoded protein is predicted to have a subcellular location within the cytosol.[6]
In the DNA, C6orf62 is 12,529 base pairs long and is located at 6q22.3.[7] It is located on chromosome 6 on position 22.3 (6q22.3). The mature mRNA sequence is 2498 base-pairs long with 5 exons and 4 intronic regions that translates a protein that is 229 amino acids long and two predicted isoforms of 160 amino acids and 200 amino acids.[8][9]
Protein
The main transcript is 229 amino acids long and is encoded from 5 exonic regions. There exists two transcript variants that are 200 amino acids and 160 amino acids long. There is a domain of unknown function (DUF4566) present in all three variants and spans positions 1–226 on the main transcript.[10] The molecular weight of C6orf62 is 27.1 kDa and its isoelectric point is at a pH of 9.24.[11] It is located subcellularly localized throughout the cytosol.[6]
Protein Interactions
| Protein | |
|---|---|
| ELAVL1 | predicted through affinity capture-RNA.[12] |
| PVRL4 | predicted through affinity capture-mass spectroscopy.[12] |
| NADH | predicted through yeast two-hybrid screening.[13] |