Phenylethylidenehydrazine

Metabolite of an antidepressant drug From Wikipedia, the free encyclopedia

Phenylethylidenehydrazine (PEH), also known as 2-phenylethylhydrazone or as β-phenylethylidenehydrazine, is a GABA transaminase inhibitor.[1][2] It is a metabolite of the antidepressant phenelzine and is responsible for its elevation of GABA concentrations.[1] PEH may contribute to phenelzine's anxiolytic effects.[3]

ATC code
  • None
Legal status
  • In general: uncontrolled
Quick facts Clinical data, Drug class ...
Phenylethylidenehydrazine
Clinical data
Drug classGABA-T inhibitor
ATC code
  • None
Legal status
Legal status
  • In general: uncontrolled
Pharmacokinetic data
Elimination half-life~12 hours[citation needed]
Identifiers
  • (1E)-(2-Phenylethylidene)hydrazine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC8H10N2
Molar mass134.182 g·mol−1
3D model (JSmol)
  • N/N=C/CC1=CC=CC=C1
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References

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