CAT RNA-binding domain
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| CAT_RBD | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 structure of the lict bacterial antiterminator protein in complex with its rna target | |||||||||
| Identifiers | |||||||||
| Symbol | CAT_RBD | ||||||||
| Pfam | PF03123 | ||||||||
| InterPro | IPR004341 | ||||||||
| SCOP2 | 1h99 / SCOPe / SUPFAM | ||||||||
| |||||||||
In molecular biology, the CAT RNA-binding domain (Co-AntiTerminator RNA-binding domain) is a protein domain found at the amino terminus of a family of transcriptional antiterminator proteins. This domain forms a dimer in the crystal structure.[1] Transcriptional antiterminators of the BglG/SacY family are regulatory proteins that mediate the induction of sugar metabolizing operons in Gram-positive and Gram-negative bacteria. Upon activation, these proteins bind to specific targets in nascent mRNAs, thereby preventing abortive dissociation of the RNA polymerase from the DNA template.[2]