CCDC88A

CCDC88A
Identifiers
Aliases	CCDC88A, APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212, coiled-coil domain containing 88A, PEHO, PEHOL
External IDs	OMIM: 609736; MGI: 1925177; HomoloGene: 41180; GeneCards: CCDC88A; OMA:CCDC88A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	55,419,895 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	29,460,808 bp
RNA expression pattern
	Top expressed in
	internal globus pallidus; ; corpus callosum; ; ventricular zone; ; ganglionic eminence; ; Achilles tendon; ; subthalamic nucleus; ; buccal mucosa cell; ; inferior ganglion of vagus nerve; ; tendon of biceps brachii; ; testicle;
	Top expressed in
	Rostral migratory stream; ; barrel cortex; ; tail of embryo; ; genital tubercle; ; lateral septal nucleus; ; lateral geniculate nucleus; ; mammillary body; ; ventromedial nucleus; ; spermatid; ; anterior amygdaloid area;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; phosphatidylinositol binding; actin binding; microtubule binding; protein kinase B binding; dynein light intermediate chain binding; G-protein gamma-subunit binding;
Cellular component	cytoplasm; Golgi apparatus; cell projection; endoplasmic reticulum; lamellipodium; membrane; cytoplasmic vesicle; cytosol; plasma membrane; cell leading edge; centrosome; centriole; cytoskeleton; ciliary basal body; COPI-coated Golgi to ER transport vesicle;
Biological process	regulation of actin cytoskeleton organization; nervous system development; DNA replication; membrane organization; cell migration; lamellipodium assembly; activation of protein kinase B activity; regulation of DNA replication; TOR signaling; regulation of protein phosphorylation; regulation of cell population proliferation; regulation of neuron projection development; cell projection organization; cytoskeleton-dependent intracellular transport; cytoplasmic microtubule organization; positive regulation of cilium assembly; positive regulation of protein localization to cilium;
	Sources:Amigo / QuickGO
Orthologs
	55704
	108686
	ENSG00000115355
	ENSMUSG00000032740
	Q3V6T2
	Q5SNZ0
	NM_001135597; NM_001254943; NM_018084; NM_001365480
	NM_176841; NM_001363368; NM_001363369
	NP_001129069; NP_001241872; NP_060554; NP_001352409
	NP_789811; NP_001350297; NP_001350298
	Wikidata
View/Edit Human	View/Edit Mouse

Girdin is a protein that in humans is encoded by the CCDC88A gene.^[5]^[6]^[7] Although its cellular function are not fully elucidated, it has been associated with glioma.^[8]