CCL15

Mammalian protein found in humans From Wikipedia, the free encyclopedia

Chemokine (C-C motif) ligand 15 (CCL15) is a small cytokine belonging to the CC chemokine family that is also known as leukotactin-1, MIP5 and HCC-2. CCL15 is expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung.[1] It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.[2][3] The human CCL15 gene spans four exons and is located in a head-to-tail orientation on chromosome 17 with the gene of another CC chemokine known as CCL14.[4]

SymbolCCL15
Alt. symbolsSCYA15, HCC-2, NCC-3, SCYL3, MIP-5, Lkn-1, MIP-1d, HMRP-2B
Quick facts chemokine (C-C motif) ligand 15, Identifiers ...
chemokine (C-C motif) ligand 15
Identifiers
SymbolCCL15
Alt. symbolsSCYA15, HCC-2, NCC-3, SCYL3, MIP-5, Lkn-1, MIP-1d, HMRP-2B
NCBI gene6359
HGNC10613
OMIM601393
PDB2HCC
RefSeqNM_032965
UniProtQ16663
Other data
LocusChr. 17 q11.2
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StructuresSwiss-model
DomainsInterPro
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